Endocrine Abstracts

Hirsutism, development of terminal body hair in women in unexpected areas, may result from different etiologies; 4.3% being nonclassical congenital adrenal hyperplasia (NCCAH) and acromegaly being one of the rarests. We here present a severe hirsutism case with acromegaly and NCCAH.Case: A 30-year-old woman with headache and visual field abnormalities was consultated by our clinic about her cranial imaging revealing a macroadenoma in pituitary localizati...

Introduction: 46 XX male syndrome generally presented as hypogonadotrophic hypogonadism.Case report: A 39-year-old man was referred to our clinic with a pituitary mass. He had a history of pituitary adenoma of 45×28×40 mm size which was found after his admission with right-sided vision loss at 2006. The hormonal analyses showed hypogonadotrophic hypogonadism without any excess hormone levels. A transcranial pituitary adenomectomy was performed....

Endocan has been suggested as a marker for endothelial dysfunction. Some evidence exists that Graves’ disease may be associated with impaired endothelial function. The aim of the study was to evaluate serum endocan, endothelial growth factor (VEGF) and carotid intima media thickness (CIMT) in patients with Graves’ disease. Thirty one newly diagnosed patients with Graves’ disease and 31 healthy volunteers with similar age and sex were examined. Serum endocan, VEG...

Aim: Sleep disturbances are widespread and closely associated with pituitary diseases, even those under long-term therapeutic management. The aim of this study was to investigate sleep quality, depression, anxiety, and physical activity in patients with non-functioning pituitary adenoma (NFPA) and determine the factors that might be associated with decreased quality of sleep.Method: Eighty-two patients with NFPAs and 82 age- and gender-matched control su...

Hyperthyroidism whether endogenous or exogenous in origin causes hemodynamic changes which associated with adverse cardiovascular outcomes. Ambulatory arterial Stiffness index (AASI) is a non invasive way of measuring arterial stiffness. Short term BP variability is derived from 24-hour ambulatory blood pressure monitoring (ABPM) recordings. BP variability and AASI are associtaed with increased cardiovascular risk.We aimed to investigate AASI and short t...

Idiopathic granulomatous hypophysitis is a very rare inflammatory disease of the pituitary gland. Primary hypophysitis represents a difficult diagnostic challenge because it can imitate pituitary adenomas clinically and radiologically. The diagnosis is usually made histologically by hypophysectomy. We herein present a rare case of idiopathic granulomatous hypopysitis diagnosed primarily by pituitary biopsy.Case: A 50-year-old female patient presented wit...

Cardiovascular deleterious effects of short term hypothyroidism are not well known. We aimed to investigate proprotein convertase subtilisin/kexin type 9 (PCSK9), soluble lectin-like oxidized LDL receptor 1 (sLOX-1) and ankle brachial index (ABI) in patients with thyroid cancer with short term overt hypothyroidism due to thyroid hormone withdrawal (THW). Twenty-one patients who require radioactive iodine (RAI) ablation or RAI scan and thirty-six age, sex, BMI similar euthyroid...

Also cytopenies can be established in the evaluation of Graves’ disease (GD), isolated thrombocytopenia is very rare. Here, we present a case of immune thrombocytopenia incidentally found in the evaluation of GD. A 48-year-old female was admitted to our hospital with palpitation and anxiousness. The thyroid function tests were concordant with thyrotoxicosis. She had two subcentimetre nodules in the right thyroid lobe. Thyroid gland had increased iodine uptake. And thyroid...

A 67–year-old female patient was transferred to our hospital from a nursing home for high capillary glucose levels and foot ulcer considered as diabetic foot infection. Her past medical history could not be obtained because of mental retardation with unknown etiology and absence of relatives.A purulent foot ulcer sized 4×3 cm was found in right heel. She also had deformities in her hands, feet, and her nose. Peripheral neuropathy was also detec...

Introduction: Mutations on menin gene are associated with multiple endocrine neoplasia type 1.Case report: Thirty-five year-old male patient was admitted to our hospital with history of recurrent syncope episodes for 5 years which were attributed to hypoglycemia. In physical examination, he had obesity and multiple papillamatous skin lesions on his abdominal region. He had no family history of similar symptoms. His laboratory eveluation was consistent wi...